06/10/08

What is the long-term prognosis for Wegener’s granulomatosis?

Nossent H. Predictors of survival and organ damage in Wegener's granulomatosis. Rheumatology (Oxford). 2002 May;41(5):572-81. [Abstract] PMID 12011383

Medical Subject Headings

  • Kidney Failure, Chronic/etiology/*mortality/pathology
  • Wegener Granulomatosis/complications/drug therapy/*mortality/pathology

Otto M. Analysis of early death based on the prediction model in Wegener's granulomatosis with pulmonary and renal involvement. J Physiol Pharmacol. 2007 Nov;58 Suppl 5(Pt 2):829-37. [Abstract] PMID 18204197

Medical Subject Headings

  • Kidney Diseases/*etiology/*mortality
  • Lung Diseases/*etiology/*mortality
  • Wegener Granulomatosis/*complications/drug therapy/*mortality

Yash Trivedi, MD, Internal Medicine Resident
Lib: RW

06/09/08

What is the VDA (vigorous diagnostic approach) for GI bleed, and what are the current management principles?

Palmer ED. The vigorous diagnostic approach to upper-gastrointestinal tract hemorrhage. A 23-year prospective study of 1,4000 patients. JAMA. 1969 Feb 24;207(8):1477-80. [Abstract] PMID 5304356 [Full text available in print only]

Medical Subject Headings

  • Gastrointestinal Hemorrhage/*diagnosis/etiology/mortality/radiography/surgery

SCOTT NM Jr. Experiences with the vigorous diagnostic approach to upper gastrointestinal hemorrhage. Ann Intern Med. 1959 Jul;51(1):89-98. [Abstract] PMID 13661791 [Full text available in print only]

Medical Subject Headings

Friedman LS. Review article: the management of lower gastrointestinal bleeding. Aliment Pharmacol Ther. 2005 Jun 1;21(11):1281-98. [Abstract] PMID 15932359

Medical Subject Headings

  • Gastrointestinal Hemorrhage/radiography/radionuclide imaging/*therapy

Affronti J. Management principles of gastrointestinal bleeding. Prim Care. 2001 Sep;28(3):557-75, vi. [Abstract] PMID 11483444

Medical Subject Headings

  • Gastrointestinal Hemorrhage/*diagnosis/epidemiology/etiology/*therapy

BONUS:

Shafi S. Hemoglobin drops within minutes of injuries and predicts need for an intervention to stop hemorrhage. J Trauma. 2007 Aug;63(2):312-5. [Abstract] PMID 17693829

Medical Subject Headings

  • Hemoglobins/*analysis
  • Hemorrhage/*blood/diagnosis/mortality/*therapy
  • *Hemostatic Techniques

Christina Collins, MD, Internal Medicine Resident
Lib: DD

06/06/08

What are the causes of recurrent pericardial effusion or pericarditis?

deFilippi C. Diagnosis and management of chronic pericardial effusions. Am J Med Sci. 2001 Aug;322(2):79-87. [Abstract] PMID 11525201

Medical Subject Headings

  • Pericardial Effusion/*diagnosis/etiology/radiotherapy/surgery/*therapy

Dr. Chauvin, Internal Medicine Resident
Lib: DD

06/04/08

What is the course for family screening for early onset of colon cancer?

Eyre HJ. American Cancer Society guidelines for the early detection of cancer, 2006. CA Cancer J Clin. 2006 Jan-Feb;56(1):11-25; quiz 49-50. [Abstract] PMID 16449183

Medical Subject Headings

  • Neoplasms/*diagnosis
  • *Societies, Medical

Rowley PT. Screening for an inherited susceptibility to colorectal cancer. Genet Test. 2004 Winter;8(4):421-30. [Abstract] PMID 15684875

Medical Subject Headings

  • Adenomatous Polyposis Coli/*etiology/*genetics/mortality
  • Colorectal Neoplasms/*etiology/*genetics/mortality
  • Colorectal Neoplasms, Hereditary Nonpolyposis/*etiology/*genetics/mortality
  • *Genetic Predisposition to Disease
  • *Genetic Screening/economics

BONUS:

Brentnall TA. Genetic testing for colon cancer. Nat Clin Pract Gastroenterol Hepatol. 2006 Dec;3(12):670-9. [Abstract] PMID 17130877

Medical Subject Headings

  • Colonic Neoplasms/*diagnosis/*genetics
  • *Genetic Screening

Dr. Escobar, Internal Medicine Resident
Lib: DD

05/28/08

What is the cost effectiveness of using amphotericin B vs. liposomal amphotericin preps?

Ludlam H. Cost-effective use of liposomal amphotericin B. Clin Lab Haematol. 2002 Oct;24(5):317-9. [Abstract] PMID 12358895

Medical Subject Headings

  • Amphotericin B/administration & dosage/*economics
  • Antifungal Agents/administration & dosage/*economics

Cagnoni PJ. Liposomal amphotericin B versus conventional amphotericin B in the empirical treatment of persistently febrile neutropenic patients. J Antimicrob Chemother. 2002 Feb;49 Suppl 1:81-6. [Abstract] PMID 11801587

Medical Subject Headings

  • Amphotericin B/*administration & dosage/adverse effects/*economics
  • Neutropenia/*drug therapy/economics
  • Phosphatidylcholines/*administration & dosage/adverse effects/*economics
  • Phosphatidylglycerols/*administration & dosage/adverse effects/*economics

Meredith DeWitt, MD, Internal Medicine Resident
Lib: DD

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